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Compared with benchmark Smoking attributable mortality (Persons 35+ yrs) Source: OHID, based on Office for National Statistics data Whilst the deaths from heart disease attributable to smoking fell from 69.8 to 58.7 deaths per 100,000 population aged 35+ years between 2013-15 and 2014-16, the rate has remained around 60 since and has been slightly higher than 60 deaths per 100,000 population in the last two years

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It stressed that "there are no safe tobacco products." Mitch Zeller, the director of the FDA's Center for Tobacco Products, said these products could potentially "help reduce nicotine dependence among addicted smokers." That said, the FDA plans to keep an eye on how 22nd Century Group proceeds

incomplete reporting by manufacturers Between 2020 and 2021, for example, the change in the number of cigarettes sold and the change in the number of smokers was roughly comparable (-10% and -8%), as shown in the figure below

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